Possible Side Effects

The most common side effects of Tyvenza (Semaglutide) may include:

Nausea

Vomiting

Diarrhoea

Abdominal Pain

Constipation

The most commonly reported side effects are related to the stomach and digestion. Follow the dose escalation schedule provided by your health care professional to help reduce the risk of these common side effects. Talk to your health care professional about any side effect that continues to bother you or don’t go away.

Tips for Managing Nausea

Some people may experience nausea while starting Tyvenza (Semaglutide) or increasing their dose. If you experience nausea, here are some general nausea tips that you might find helpful:

Eat bland, low- fat foods, like crackers, toast, and rice.

Eat foods that contain water, like soups and gelatin.

Avoid fried, greasy, or sweet foods.

Avoid lying down after you eat.

Go outdoors for fresh air.

Eat more slowly.

Drink clear beverages (water, ginger ale, clear broth, tea, and sports drinks)

Dose titration related side effects

The most commonly reported side effects were related to the stomach and digestion. These side effects were reported more frequently when starting to take Tyvenza (Semaglutide) or when increasing the dose. Talk to your health care professional about any side effect that continues to bother you.

Taking Tyvenza (Semaglutide) in the morning, afternoon, or night

Tyvenza (Semaglutide) should be taken once a week, on the same day every week, at any time of the day. Tyvenza (Semaglutide) may be taken with or without food. You may change the day of the week you take Tyvenza (Semaglutide), as long as your last dose was taken 3 or more days before.

Reaction at the injection site

After injecting Tyvenza exactly as instructed, some people may experience some bleeding at the injection site. Press on the area lightly with a gauze pad or cotton ball. Do not rub the area.

You may inject under the skin of your stomach/abdomen, thigh, or upper arm. Be sure to change the injection site after each weekly injection, and do not use the same site for each injection. Talk to your health care professional about any irritation or reaction at the injection site that bothers you or doesn’t go away.